Hemodynamic Changes in Fetal Lamb in Utero in Response to Asphyxia, Hypoxia, and Hypercapnia

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Hemodynamic changes in fetal lamb in uteroin response to asphyxia, hypoxia, and hypercapnia.

• "When fetaJ asphyxia or hypoxia is induced by reduction of uterine and umbilical circulations oi" by administration of a gas mixture of low oxygen content to the mother, there is an increase in the fetal arterial pressure." The effects on the fetal heart rate appear to be variable. Bradycardia has been observed by several investigators.*~ Born et al. noted that the changes in heart rate depen...

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Cardiovascular response of the neonatal lamb to hypoxia and hypercapnia.

STAHLMAN, M.,J. GRAY, W.C. YOUNG,AND F.M. SHEPARD. Cardiovascular response of the neonatal lamb to hypoxia and hypercapnia. Am. J. Physiol. 213(4): 899-904. 1967.-The effects of hypoxia and hypercapnia on the circulatory dynamics of the unanesthetized newborn lamb were evaluated. Hypoxia produced by inhalation of 8a/, 02 caused a marked increase in pulmonary arterial pressure and pulmonary vasc...

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Prostaglandin control of the renal circulation in response to hypoxemia in the fetal lamb in utero.

We studied the effects of 10-minute periods of hypoxemia in unanesthetized fetal lambs in utero instrumented for measurements of arterial pressure and renal and iliac blood flows. Fetal hypoxemia, induced by delivering a hypoxic gas mixture to the ewe, was characterized by a reduction in fetal PaO2 from 20.1 +/- 1.4 to 8.8 +/- 1.0 mm Hg (mean +/- SE). The fetus responded with bradycardia and pe...

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Hemodynamic and ventilatory response to different levels of hypoxia and hypercapnia in carotid body-denervated rats

OBJECTIVE Chemoreceptors play an important role in the autonomic modulation of circulatory and ventilatory responses to changes in arterial O(2) and/or CO(2). However, studies evaluating hemodynamic responses to hypoxia and hypercapnia in rats have shown inconsistent results. Our aim was to evaluate hemodynamic and respiratory responses to different levels of hypoxia and hypercapnia in consciou...

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Quantitative evaluation of hemodynamic parameters during acute alveolar hypoxia and hypercapnia in the isolated ventilated-perfused rabbit lung

Introduction: Acute respiratory disorders such as obstructive pulmonary diseases and hypoventilation may lead to alveolar hypoxia and hypercapnia which their effects on pulmonary vascular beds are controversial. The aim of this study was to establish the isolated perfused lung setup and investigate the effects of alveolar hypoxia and hypercapnia on pulmonary vascular resistance. Methods: White ...

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ژورنال

عنوان ژورنال: Circulation Research

سال: 1962

ISSN: 0009-7330,1524-4571

DOI: 10.1161/01.res.11.3.423